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- Wife
- Soh Puay
- Sons
- IR Kuan Kain
Kuan Yew Kee
Kuan Yew Keong
Kuan Yew Chuan
Kuan Yew Chong
Kuan You Joo
- Daughters-in-Law
- Jenny Tan Siew Luan
Lim Lei Chin
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Ong Shaw Peng
Betty Ling Yieng
Koh Mei Lan
- Daughters
- Kuan Siew Chin
Kuan Poh Chin
- Sons-in-Law
- Lee Chow Aik
Ong Seng Teik
- Grandsons
- Dr Kenneth Kuan Boon Keat
Dr Kevin Kuan Boon Sen
Colin Kuan Heng Jian
Calvin Kuan Heng Qing
Jeffrey Kuan Boon Qian
Jacky Kuan Boon Han
Dr Ian Kuan Boon Jin
Isaiah Kuan Boon Yi
Lee Jun Quan
Edmond Ong Chin Yao
Nicholas Ong Chin Kun
- Granddaughters-in-Law
- Dr Ding Yee Lein
Dr Phyllis Yam Rui-Lin
- Granddaughters
- Dr Kathryn Kuan Huei Hern
Christine Kuan Huei Ern
Cathy Kuan Huei Han
Sally Kuan Hui Jin
Janet Kuan Hui Fang
Dr Isabelle Kuan Hui San
Ivana Kuan Hui Sze
Neriah Kuan Hui Yi
Lee Yi Wen
Dr Emily Ong Hui Xian
Esther Ong Shu Jun
- Grandsons-in-Law
- Dr Wong Jsun Loong
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Dr Derek Zhu Xiao
- Great Grandson
- Lucas Kuan Yeok Jin
- Great Granddaughters
- Sophie Kuan Ru Xin
Grace Wong Yi Yuen