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- Wife:
- Lorna Lim Siew Keng (deceased)
- Brothers:
- Khoo Swee Tiong (deceased)
Tan Kim Hock (deceased)
Willie Khoo Swee Chiang (deceased)
Khoo Swee Goon
Khoo Swee Ban
Khoo Swee Lam (deceased)
Khoo Swee Guan (deceased)
- Spouses:
- Ong Yoke Lin
Lee Lye Neo (deceased)
Lai Ying (deceased)
Koh Tiew Neo
Lim Guat Ngoh
-
Teoh Chai Choo
- Sisters:
- Nellie Khoo Swee Sim (deceased)
Khoo Swee Gim (deceased)
Khoo Swee Lai
Khoo Swee Imm
- Spouses:
- Cheong Sian Tong (deceased)
Ng Yoke Chee (deceased)
Lee Kee Puan (deceased)
Wilson Yau Kum Yuen (deceased)
- Sons:
- Augustus Khoo Ghi Hai
Jeffrey Khoo Ghi Chuan
- Spouses:
- Chan Wei Yin
Cheng Lee Lin